ISSN (ONLINE): 3107-7862
jkpo; irf;fpahl;hp [h;dy; mwk; kdey kUj;Jtkid / [dthp-khh;r; 2026
18
    
   
 
Thiamine

 
B1

 
   
    
    
 
B1

   
 
Acute Wernicke Syndrome


Wernicke Syndrome
  
 

Confusion
 
  
    
  


Ataxia
   
  

Nystagmus
 
  
(vertical and
horizontal nystagmus).
  
    
  
  
Wernicke Encephalopathy
  
   
  
Wernicke encephalopathy


Thiamine injection

   
   
    
   
    

Korsakoff Syndrome
 
   

Wernicke Korsakoff Syndrome


Thiamine 500mg IV
   
   
Tablet
 
    

Magnesium
 

Magnesium
 

thiamine
 
 
Wernicke Korsakoff Syndrome
  
Thiamine

Magnesium
 

   
  
   
  
  
  
 
thiamine
 
Wernicke Korsakoff syndrome

Wernicke Encephalopathy

   
  
Delirium

    
   
     
   
  
  
   
   
   
   
   
   
Wernicke-Korsakoff Syndrome
Causes, Presentation, Prevention and Management
       
Tamil Psychiatry Journal, Vol-2, Issue-1, Jan-Mar 2026, Page 18-21
ISSN (ONLINE): 3107-7862
jkpo; irf;fpahl;hp [h;dy; mwk; kdey kUj;Jtkid / [dthp-khh;r; 2026
19
Wernicke Encephalopathy

  
   
  
Physiotherapy
  
Thiamine
 
    
   
    
    
Dietician
   

Wernicke Encephalopathy

  
 
Bacterial infections
 
    
    
 
Antibiotic
 
  
UTI, Respiratory tract infection,
sepsis, meningitis
  
   
     

Delirium
  
   
 
Wernicke Korsakoff


(cognition)
  

(poor attention & concentration)

   
   

(poor Speech);
 
   
 
(Anterograde amnesia),
    
    
   

Korsakoff Dementia
  

Wernicke Encephalopathy

   
    
   
cognition
     
  
Korsakoff syndrome - a case study
    
     
    
    
   
   
   
   
  
  
   
   
   
   
   
     
   
  
Wernicke
Encephalopathy
 

Thiamine
 
Magnesium
   
   
   
     
    
   

(Cognition)
 
   
    
    
     
    
     
 
Amnesia
 
    

confabulation
  
    
    
    
   
   
Korsakoff syndrome
 
 

MRI scan

occipital lobe, parietal lobe

temporal lobe
 
gliosis
ISSN (ONLINE): 3107-7862
jkpo; irf;fpahl;hp [h;dy; mwk; kdey kUj;Jtkid / [dthp-khh;r; 2026
20
   
SW
  
MRI

  
  
Korsakoff
Syndrome
 
Korsakoff syndrome
 
   
   
Korsakoff
  
   

Wernicke Encephalopathy
  
   
  
Korsakoff syndrome
 

Thiamine

     

thiamine absorption


   
  
thiamine
 
   
    
   
thiamine
 
  

metabolism

thiamine

  
Thiamine

pyruvate
 
   
  
  
  
lactate

 
(edema)
 
gliosis
   
Anterior nucleus of thalamus, corpus callosum and
Mamillary body
   
   
Korsakoff syndrome

Cognition


Cerebellum

Degeneration

Korsakoff

Ataxia
   
 

  
  
  
 
Detox
 
   
wernicke encephalopathy
   
  
 
  
Thiamine

Magnesium

Multivitamin
   


vitamin
 
   
Wernicke -
Korsakoff syndrome
  
   
ISSN (ONLINE): 3107-7862
jkpo; irf;fpahl;hp [h;dy; mwk; kdey kUj;Jtkid / [dthp-khh;r; 2026
21

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chronic alcoholics: identification of Wernicke's encephalopathyJ. Neurol. Neurosurg. Psychiatry,
62(1) (1997), pp. 51-60
2. E.Oudman, J.W. Wijnia, M.J. Oey, M.van Dam, A. Postma Wernicke-Korsakoff syndrome
despite no alcohol abuse: a summary of systematic reports J. Neurol. Sci., 15 (426) (2021),
Article 117482
3. A.D. Thomson, I. Guerrini, E.J.Marshall The evolution and treatment of Korsakoff's syndrome
Neuropsychol. Rev., 22 (2) (2012), pp. 81-92
4. J.G.L. A-Tjak, N. Morina, M. Topper, P.M.G Emmelkamp One year follow-up and mediation in
cognitive behavioral therapy and acceptance and commitment therapy for adult depression BMC
Psychiatry, 21 (1) (2021), p. 41
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