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Acetylcholine
Acetylcholine
50
2050-
Alzheimer's Dementia
Vascular Dementia
Fronto Temporal Dementia,
Lewy Body Dementia
Alzheimers dementia
60%-80%
Alzheimer's
Dementia
Alzheimers Dementia
65
60
plaque
tangle
Plaque
plaque
amyloid protein
Tangle
tau protein
APOE (ApolipoProtein E4)
Alzheimer's
Dementia-
Dementia
Causes, Symptoms, Types and Treatment
Tamil Psychiatry Journal, Vol-2, Issue-1, Jan-Mar 2026, Page 22-26
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'fan'
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(delusion)
80%
90%
Citalopram, Lorazepam, Oxazepam (Short Acting
Benzodiazepines), Clozapine, Carbamazepine (304mg/day),
Divalproex Sodium 826mg/day, Risperidone 1mg/day,
Olanzapine 5mg/day
Zolpidem
5mg (non-benzodiazepine medications)
Trazodone
(Sedative antidepressant)
Psychotic
ntipsychotic
(Depression)
SSRI, SNRI, NASSA, NRI
Tricyclic Antidepressant
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Tricyclic
CT
lzheimer
Dementia-
CT Scan
MRI Scan
Vascular Dementia
-
Complete Blood Count
B12 level
Folate level
TSH Thyroid function test
Vitamin D
Cholesterol Level
VASCULAR DEMENTIA
Vascular Dementia
stroke
ascular Dementia
stroke
(Antihypertensive Tablets), cholesterol
aspirin
cholesterol,
stroke
vascular dementia
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REFERENCE:
1. Parnetti, L., Chipi, E., Salvadori, N., D'Andrea, K., & Eusebi, P. (2019). Prevalence and risk of
progression of preclinical Alzheimer's disease stages: a systematic review and meta-
analysis. Alzheimer's research & therapy, 11(1), 7. https://doi.org/10.1186/s13195-018-0459-7
2. Tay, L. X., Ong, S. C., Tay, L. J., Ng, T., & Parumasivam, T. (2024). Economic Burden of Alzheimer's
Disease: A Systematic Review. Value in health regional issues, 40, 1–12.
https://doi.org/10.1016/j.vhri.2023.09.008
3. Blackman, J., Swirski, M., Clynes, J., Harding, S., Leng, Y., & Coulthard, E. (2021). Pharmacological
and non-pharmacological interventions to enhance sleep in mild cognitive impairment and mild
Alzheimer's disease: A systematic review. Journal of sleep research, 30(4), e13229.
https://doi.org/10.1111/jsr.13229
4. Mühlbauer, V., Möhler, R., Dichter, M. N., Zuidema, S. U., Köpke, S., & Luijendijk, H. J. (2021).
Antipsychotics for agitation and psychosis in people with Alzheimer's disease and vascular
dementia. The Cochrane database of systematic reviews, 12(12), CD013304.
https://doi.org/10.1002/14651858.CD013304.pub2
5. Coley, N., Giulioli, C., Aisen, P. S., Vellas, B., & Andrieu, S. (2022). Randomised controlled trials for
the prevention of cognitive decline or dementia: A systematic review. Ageing research reviews, 82,
101777. https://doi.org/10.1016/j.arr.2022.101777
6. Fu, Q., DeJager, J., & Gardner, E. M. (2024). Supplementation and Mitigating Cognitive Decline in
Older Adults With or Without Mild Cognitive Impairment or Dementia: A Systematic
Review. Nutrients, 16(20), 3567. https://doi.org/10.3390/nu16203567
7.
Chen, Y., Lai, M., & Tao, M. (2024). Evaluating the efficacy and safety of Alzheimer's disease drugs: A
meta-analysis and systematic review. Medicine, 103(16), e37799.
https://doi.org/10.1097/MD.0000000000037799
